Chemical sanitization of purified water supply loop

1.0 OBJECTIVE
To lay down a procedure for Chemical sanitization of purified water system loop when the microbial limits are above alarming range.
2.0 SCOPE
This SOP is applicable to Formulations Units
2.1.0 AREAS
Purified water plant.
3.0 RESPONSIBILITY
Technical officer / Executive (production)
4.0 ACCOUNTABILITY
Manager production.
5.0 PROCEDURE
5.1 Precautions
5.2 Pre – Start up
5.3 Operation
5.1 Precautions
5.1.1 Be careful while handling the chemicals.
5.1.2 Wear gloves and nose mask before handling the chemicals.
5.2 Pre-Start up
5.2.1 Ensure the availability of D.M water & Purified water.
5.2.2 Ensure the availability of all chemicals and accessories.
5.2.3 Before starting the pumps P2 / P3 make sure that all user point valves should be closed.
5.3 Operation
5.3.1Collect 600 lts of purified water into 1500 lts storage tank. Keep the U.F system in re-circulation mode by opening the valve V24 and closing the valve V23.
5.3.2 Pour 15 kgs of NaoH (100%)in the tank through manhole. Mix the NaoH with water using S.S rod. Ensure that man hole is closed.
5.3.3 Start the pumps P2/ P3.
5.3.4 Re-circulate the solution through entire loop for 30 minutes.
5.3.5 After 30 minutes drain the solution through all user points and from the storage tank.
5.3.6 Collect the purified water in the storage tank by opening the valve V23 and closing the valve V24.
5.3.7 Start the pumps P2/ P3 when the water level was above 600 mm WC. Flush the entire pipe line for 30 minutes.
5.3.8 Inform the Quality control for collecting the sample from all user points. Go for next chemical after getting approval form Quality control.
5.3.9 Collect the 600 lts of purified water in the 1500 lts storage tank keep the U.F system in re-circulation mode by opening the valve V24 and closing the valve V23.
5.3.10 Pour 20 lts of Nitric Acid (69 %) in the tank through manhole. Ensure that manhole was closed.
5.3.11 Follow the points from 5.3.3 to 5.3.8.
5.3.12 Collect 600 lts of purified water into 1500 lts storage tank. Keep the U.F system in re-circulation mode by opening the valve V24 and closing the valve V23.
5.3.13 Pour 25 kgs of Citric Acid (100% ) in the tank through manhole. Ensure that manhole was closed.
5.3.14 Follow the points from 5.3.3 to 5.3.8.
5.3.15 Collect 600 lts of purified water into 1500 lts storage tank. Keep the U.F system in re-circulation mode by opening the valve V24 and closing the valve V23.
5.3.16 Pour 30 lts Hydrogen peroxide ( 100%) in the tank through manhole. Ensure that manhole was closed.
5.3.17 Follow the points 5.3.3 to 5.3.8.
5.3.18 After completion of the chemical sanitization continue the hot water sanitazation according to the SOP No.: XXXXX