SEMI-AUTOMATIC LIQUID VIAL FILLING AND RUBBER STOPPERING MACHINE

1. Objective:

To lay down a standard operating procedure for Semi-Automatic Liquid vial filling & Rubber stoppering Machine.

2. Scope:

This procedure provides a standard method of operation and handling of the Automatic Liquid vial filling & Rubber stoppering Machine.

3. Responsibility:

§ Machine operator.

§ Senior Chemist.

§ Head - Production.

4. Procedure:

4.1. Check and make sure that entire machine parts are cleaned as per SOP No: P/P/012.

4.2. Make sure that Line clearance is duly checked and signed by QA Personal as per SOP No:P/P/047

4.3. Fill the solution to be filled, in the pressurized tank.

4.4. Connect the piston bottom hose to pressurized tank and piston top hose with the filling needles.

4.5. Adjust the speed of the conveyor according to the movement of piston in such a way that both speeds should be equal to avoid the spillage of the filling solution & breakage of the vial.

4.6. Set the required volume to be filled by adjusting the volume adjustment screw in the piston. Switch on the machine.

4.7. Piston will suck the solution from the tank and fill it in vial through the filling needle.

4.8. The filled vials will be transferred to the sealing section through the conveyor.

4.9. In the sealing section, feed the seals into the sealing hopper and switch on the machine.

4.10. The filled vials to be sealed will come to the turret through the conveyor.

4.11. The seals will sit on the neck of the filled vials through the chute from the hopper. After that the sealing fingers will press the seals.

4.12. Collect the sealed vials and send it to labeling section after getting approval from QC for Leak Test.