Recording and monitoring of differential air pressure

1.0 OBJECTIVE
To lay down a procedure for recording and monitoring of differential air pressure.
2.0 SCOPE
All Modules, Dispensing cubicles, & Primary packing areas.
3.0 RESPONSIBILITY
Concerned officer.
4.0 ACCOUNTABILITY
Concerned executive
5.0 PROCEDURE
5.1 Record the differential pressure between outer corridor and gowning rooms twice daily (Locations of manometers given in Annexure-I ).
5.1.1 Pressure differential limit is 1.0 -1.6mm of water guage.
5.2 Record the differential pressure between Inner corridor and process rooms twice daily (Locations of manometers given in Annexure-I ).
5.2.1 Pressure differential limit is 0.6 -1.0 mm of water guage.
5.3 If any discrepency is observed report to maintenance for corrective action.
5.4 Stop the process till the corrective action is taken.
5.5 If the material is stored in open containers, seal the containers with film / lids.
5.6 Once the corrective action is taken, record pressure differential and start the process.
ANNEXURE - I
LOCATIONS OF MANOMETERS
A. Manometers between outer corridor & adjcent areas

B. Manometers between Inner Corridor / Air lock and Process rooms.